By University of Western Ontario October 4, 2019
Scientists at Western University demonstrate when it comes to first time the molecular mechanisms in the office that can cause cannabidiol , or CBD, to block the psychiatric side effects brought on by tetrahydrocannabinol (THC), the key psychoactive chemical in cannabis.
It was previously shown that strains of cannabis with high quantities of THC and lower levels of CBD could cause increased psychiatric impacts, including paranoia, anxiety, and addictive-behaviors, but why that has been occurring had not been fully comprehended.
Steven Laviolette, PhD, along with his research group utilized rats to analyze the part of a molecule when you look at the brain’s hippocampus called extracellular-signal kinase that is regulatedERK) which triggers the neuropsychiatric aftereffects of THC.
Steven Laviolette investigates the part of ERK within the brain’s hippocampus which causes the neuropsychiatric aftereffects of THC. Credit: Western University
“For years we now have understood that strains of cannabis saturated in THC and reduced in CBD had been prone to cause psychiatric side effects,” said Laviolette, a professor at Western’s Schulich class of Medicine & Dentistry. […]